Adverse effects after vaccination against SARS-CoV-2 (COVID-19) in Down syndrome adults
DOI:
https://doi.org/10.5585/22.2023.23794Keywords:
Down syndrome, Vaccines, COVID-19, Adverse effects.Abstract
Introduction: Comorbidities in adults with Down syndrome are common making them a risk group for COVID-19. Thus, vaccinating against COVID-19 becomes necessary, but requires care against possible side effects.
Objective: To investigate possible adverse effects after vaccination against COVID-19 in adults with Down Syndrome (DS).
Methodology: Descriptive study in which ninety-seven adults diagnosed with DS were interviewed using a questionnaire containing seventeen questions related to personal and historical data, and seven questions related to vaccination.
Results: The most applied vaccine was AstraZeneca (94%), Pfizer (4%), and CoronaVac (2%); 74% of the subjects had adverse effects, the most frequent after the first dose being pain at the injection site (65.3%), fever (37.9%), muscle pain (37.8%), malaise (29.5%); in the second dose there was a decrease in these adverse effects; 95% of symptoms disappeared after the first 24 hours following application.
Conclusion: More than half of the individuals interviewed had adverse effects after the application of the first dose of the vaccine, decreasing with the second dose; the most frequent was pain at the site of application.
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