Validity and Responsiveness of the Manchester Fatigue Scale in Post-COVID

Authors

DOI:

https://doi.org/10.5585/23.2024.26134

Keywords:

Fatigue, Post-Acute COVID-19 Syndrome, Symptom Assessment

Abstract

Objective: This study investigates the Manchester COPD Fatigue Scale's (MCFS) validity and responsiveness in individuals after hospitalization due to COVID-19.
Methods: A longitudinal observational study included 53 adults diagnosed with COVID-19. Modified Medical Research Council dyspnea scale (mMRC), Six-Minute Step Test (6MST), Saint George's Respiratory Questionnaire (SGRQ), and Hospital Anxiety and Depression Scale (HADS) were assessed. The measurement properties tested were concurrent, convergent, discriminant validities, and responsiveness.
Results: The MCFS showed concurrent, convergent, and discriminant validity, with moderate to strong significant correlations with fatigue (rs=0.57), symptoms (rs=-0.27), exercise performance (rs=0.39), depression (rs=0.67), and dyspnea (rs=0.44) measures. The instrument exhibited internal responsiveness with reduced fatigue scores three months after hospital discharge (median total score from 14.5 to 5.0,p<0.001). External responsiveness was shown through associations between MCFS scores and dyspnea changes.
Conclusion: The MCFS is a valid and responsive tool for physicians and researchers in effectively identifying, monitoring, and managing post-COVID-19 fatigue.

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Author Biographies

Mara Galdino Müller, Universidade Federal de Juiz de Fora

Physiotherapist, specialist in Respiratory Physiotherapy, Master in Rehabilitation Sciences and Functional Physical Performance from the Federal University of Juiz de Fora.

Caroline Valle Americano, Federal University of Juiz de Fora

Graduation Program on Rehabilitation Sciences

Carlos Alberto Mourão Júnior , Federal University of Juiz de Fora

Physician, PhD in Sciences from the Federal University of São Paulo. He served as a professor at the Federal University of Juiz de Fora.

Cyntia Pace Schmitz Corrêa, Federal University of Juiz de Fora

Physiotherapist, PhD in Public Health from the Federal University of Juiz de Fora, Assistant Professor at the Faculty of Physiotherapy of the Federal University of Juiz de Fora.

Felipe Meirelles de Azevedo, Federal University of Juiz de Fora

Physiotherapist, specialist in Intensive Care and Cardiovascular Therapy, Master in Rehabilitation Sciences and Functional Physical Performance from the Federal University of Juiz de Fora.

Rafaella Polato, Federal University of Juiz de Fora

Physiotherapist, Master in Rehabilitation Sciences and Functional Physical Performance from the Federal University of Juiz de Fora.

Leandro Ferracini Cabral , Federal University of Juiz de Fora

Physiotherapist, PhD in Sciences from the Federal University of Rio de Janeiro, Associate Professor at the Faculty of Physiotherapy of the Federal University of Juiz de Fora.

Cristino Carneiro Oliveira , Federal University of Juiz de Fora

Physiotherapist, PhD in Physiotherapy from the University of Melbourne, Australia, Assistant Professor at the Faculty of Physiotherapy of the Federal University of Juiz de Fora.

Anderson José , Federal University of Juiz de Fora

Physiotherapist, PhD in Rehabilitation Sciences from Universidade Nove de Julho, Assistant Professor at the Faculty of Physiotherapy of the Federal University of Juiz de Fora.

Carla Malaguti, Universidade Federal de Juiz de Fora

Physiotherapist, PhD in Sciences from the Federal University of São Paulo, Associate Professor at the Faculty of Physiotherapy of the Federal University of Juiz de Fora.

References

Fernández-de-las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, et al. Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: A systematic review and meta-analysis. Eur J Intern Med. 2021;92:55-70. doi:10.1016/j.ejim.2021.06.009

Hartung TJ, Neumann C, Bahmer T, et al. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine. 2022;53:101651. doi:10.1016/j.eclinm.2022.101651

Webster K, Cella D, Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) Measurement System: properties, applications, and interpretation. Health Qual Life Outcomes. 2003;1(1):79. doi:10.1186/1477-7525-1-79

Al-shair K, Kolsum U, Berry P, et al. Development, dimensions, reliability and validity of the novel Manchester COPD fatigue scale. Thorax. 2009;64(11):950-955. doi:10.1136/thx.2009.118109

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis. 1987;40(5):373-383. doi:10.1016/0021-9681(87)90171-8

Pereira CA de C, Sato T, Rodrigues SC. Novos valores de referência para espirometria forçada em brasileiros adultos de raça branca. Jornal Brasileiro de Pneumologia. 2007;33(4):397-406. doi:10.1590/S1806-37132007000400008

Vieira, GC. Tradução para a língua portuguesa, adaptação cultural e análise das propriedades de medidas da escala de fadiga de Manchester para uso em indivíduos com doença pulmonar obstrutiva crônica no Brasil. Dissertação 2022. doi: https://doi.org/10.34019/ufjf/di/2022/00183

Kovelis D, Segretti NO, Probst VS, Lareau SC, Brunetto AF, Pitta F. Validação do Modified Pulmonary Functional Status and Dyspnea Questionnaire e da escala do Medical Research Council para o uso em pacientes com doença pulmonar obstrutiva crônica no Brasil. Jornal Brasileiro de Pneumologia. 2008;34(12):1008-1018. doi:10.1590/S1806-37132008001200005

da Costa JN, Arcuri JF, Goncalves IL, et al. Reproducibility of Cadence-Free 6-Minute Step Test in Subjects with COPD. Respir Care. 2014;59(4):538-542. doi:10.4187/respcare.02743

Jones PW, Quirk FH, Baveystock CM. The St George’s Respiratory Questionnaire. Respir Med. 1991;85:25-31. doi:10.1016/S0954-6111(06)80166-6

Marcolino JÁM, Suzuki FM, Alli LAC, Gozzani JL, Mathias LA da ST. Medida da ansiedade e da depressão em pacientes no pré-operatório. Estudo comparativo. Rev Bras Anestesiol. 2007;57(2):157-166. doi:10.1590/S0034-70942007000200004

Huang C, Huang L, Wang Y, et al. RETRACTED: 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. The Lancet. 2021;397(10270):220-232. doi:10.1016/S0140-6736(20)32656-8

Naik H, Shao S, Tran KC, et al. Evaluating fatigue in patients recovering from COVID-19: validation of the fatigue severity scale and single item screening questions. Health Qual Life Outcomes. 2022;20(1):170. doi:10.1186/s12955-022-02082-x

Twomey R, DeMars J, Franklin K, Culos-Reed SN, Weatherald J, Wrightson JG. Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study. Phys Ther. 2022;102(4). doi:10.1093/ptj/pzac005

Noakes TD, St Clair Gibson A, Lambert E V. From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions. Br J Sports Med. 2005;39(2):120-124. doi:10.1136/bjsm.2003.010330

Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group. Ann Intern Med. 1994;121(12):953-9. doi: 10.7326/0003-4819-121-12-199412150-00009

Sandler CX, Wyller VBB, Moss-Morris R, Buchwald D, Crawley E, Hautvast J, Katz BZ, Knoop H, Little P, Taylor R, Wensaas KA, Lloyd AR. Long COVID and Post-infective Fatigue Syndrome: A Review. Open Forum Infect Dis. 2021;8(10):ofab440. doi: 10.1093/ofid/ofab440.

Yue Y, Li L, Liu R, et al. The dynamic changes of psychosomatic symptoms in three waves of COVID-19 outbreak and fatigue caused by enduring pandemic in China. J Affect Disord. 2023;331:17-24. doi:10.1016/j.jad.2023.03.032

Daynes E, Baldwin MM, Annals M, Gardiner N, Chaplin E, Ward S, Greening NJ, Evans RA, Singh SJ. Changes in fatigue symptoms following an exercise-based rehabilitation programme for patients with long COVID. ERJ Open Res. 2024;10(4):00089-2024. doi: 10.1183/23120541.00089-2024.

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Published

2024-10-14

How to Cite

1.
Müller MG, Americano CV, Mourão Júnior CA, Corrêa CPS, Azevedo FM de, Polato R, et al. Validity and Responsiveness of the Manchester Fatigue Scale in Post-COVID. Cons. Saúde [Internet]. 2024 Oct. 14 [cited 2024 Dec. 22];23(1):e26134. Available from: https://periodicos.uninove.br/saude/article/view/26134

Issue

v. 23 (2024 - Fluxo contínuo)

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Artigos

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Copyright (c) 2024 Mara Galdino Müller, Caroline Valle Americano, Carlos Alberto Mourão Júnior , Cyntia Pace Schmitz Corrêa, Felipe Meirelles de Azevedo; Rafaella Polato; Leandro Ferracini Cabral , Cristino Carneiro Oliveira , Anderson José , Carla malaguti

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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