Wound healing using Chenopodium ambrosioides (mastruz) extract and sterile secondary coverage in rats

Abstract

Introduction: Mastruz (Chenopodium ambrosioides) is one of the most used plants in folk medicine. Objectives: To verify the healing of skin wounds treated with mastruz with and without cover. Methods: Forty-five Wistar rats, divided into three groups, were used. The wounds of the animals were treated as follow: in group 1, with a 0.9% saline solution; in group 2, with mastruz extract; and in group 3, with mastruz extract and bandaging. They were evaluated in the 4th, 7th and 14th postoperative day. Results: The animals treated with mastruz without bandaging showed a better wound contraction in the 4th and 7th day. In the 14th day there was not a significant difference in the wound contraction, and the histological findings showed moderate inflammation, better matrix organization and partial wound reepithelization in all groups. Conclusion: Chenopodium ambrosioides (mastruz) extract favored open skin wound healing in rats.