Effects of Passiflora edulis S. in the healing process burns induced in mice

Abstract

Introduction: Burns lead to partial or total destruction of the exposed tissue. The Passiflora edulis S. treats skin inflammation. Objective: Evaluating the effects of the Passiflora edulis S. extract in burns induced in mice. Methods: 30 mice, randomly divided in three equal groups: Control (C), Burns (Q) and Burns treated with the Passiflora edulis S. extract (QT) split in seven and fourteen days. The qualitative evaluation was based on the presence of inflammatory cells, fibroblasts and organization of the collagen fibers and the quantitative was based on the Image J® program, function “cell counter”. Results: A reduction of the amount of inflammatory cells and a raise on fibroblasts was noted on the QT group after seven days. After the fourteen days it was observed an organization of the collagen fibers and a significant difference (p<0,001) on the fibroblasts number when related to the Q and QT groups. Conclusion: The Passiflora edulis S. extract accelerated the repair process of the induced burns on mice.