Exercício físico e comprimento dos telômeros: uma revisão sistemática nas disfunções crônico-degenerativas

Gustavo de Moraes Silva; Flavio de Souza Araujo; Alfredo Anderson Teixeira-Araújo; Reginaldo Luiz do Nascimento; Geovani Alves dos Santos; Sérgio Rodrigues Moreira

doi:10.5585/conssaude.v17n2.8037

Authors

Gustavo de Moraes Silva Universidade Federal do Vale do São Francisco
Flavio de Souza Araujo Universidade Federal do Vale do São Francisco
Alfredo Anderson Teixeira-Araújo Centro Universitário Dr. Leão Sampaio - UNILEÃO
Reginaldo Luiz do Nascimento Universidade Tiradentes – UNIT
Geovani Alves dos Santos Universidade Federal do Vale do São Francisco
Sérgio Rodrigues Moreira Universidade Federal do Vale do São Francisco

DOI:

https://doi.org/10.5585/conssaude.v17n2.8037

Keywords:

Exercise, Telomeres, Metabolic diseases.

Abstract

Introduction: Telomeres are located at the ends of chromosomes and consist of DNA sequences and associated proteins. Physical exercise seems to be related to a greater telomeres length, but little is known about its impact on the telomere dynamics of people with chronic degenerative dysfunctions. Purpose: Systematically review the literature on the effect of exercise on the telomeres length in people with chronic degenerative disorders. Methods: Searches were carried out by two independent researchers in the databases Pubmed, Scopus, Lilacs e Cochrane Controlled Trials Database, analyzing publications in the English and Portuguese language. Results: A total of 845 studies were found, of which four met the eligibility criteria and followed up for synthesis. Conclusion: Although shortening of telomeres is related to lifestyle, genetic inheritance, and diseases of aging, still unclear physical exercise can attenuate such a shortening process significantly in individuals with chronic-degenerative dysfunctions such as overweight and diabetes.