Physical exercise and telomere length: a systematic review in chronic-degenerative dysfunctions

Authors

  • Gustavo de Moraes Silva Universidade Federal do Vale do São Francisco
  • Flavio de Souza Araujo Universidade Federal do Vale do São Francisco
  • Alfredo Anderson Teixeira-Araújo Centro Universitário Dr. Leão Sampaio - UNILEÃO
  • Reginaldo Luiz do Nascimento Universidade Tiradentes – UNIT
  • Geovani Alves dos Santos Universidade Federal do Vale do São Francisco
  • Sérgio Rodrigues Moreira Universidade Federal do Vale do São Francisco

DOI:

https://doi.org/10.5585/conssaude.v17n2.8037

Keywords:

Exercise, Telomeres, Metabolic diseases.

Abstract

Introduction: Telomeres are located at the ends of chromosomes and consist of DNA sequences and associated proteins. Physical exercise seems to be related to a greater telomeres length, but little is known about its impact on the telomere dynamics of people with chronic degenerative dysfunctions.  Purpose: Systematically review the literature on the effect of exercise on the telomeres length in people with chronic degenerative disorders. Methods: Searches were carried out by two independent researchers in the databases Pubmed, Scopus, Lilacs e Cochrane Controlled Trials Database, analyzing publications in the English and Portuguese language. Results: A total of 845 studies were found, of which four met the eligibility criteria and followed up for synthesis. Conclusion: Although shortening of telomeres is related to lifestyle, genetic inheritance, and diseases of aging, still unclear physical exercise can attenuate such a shortening process significantly in individuals with chronic-degenerative dysfunctions such as overweight and diabetes.

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Published

2018-06-29

How to Cite

1.
Silva G de M, Araujo F de S, Teixeira-Araújo AA, Nascimento RL do, Santos GA dos, Moreira SR. Physical exercise and telomere length: a systematic review in chronic-degenerative dysfunctions. Cons. Saúde [Internet]. 2018 Jun. 29 [cited 2024 Jul. 3];17(2):211-8. Available from: https://periodicos.uninove.br/saude/article/view/8037

Issue

Section

Literature reviews