Relationship between lung function and muscle properties in patients with chronic obstructive pulmonary disease

Abstract

Objective: To determine the interrelationships between lung function and attributes mass and muscle strength in patients with chronic obstructive pulmonary disease (COPD). Method: 22 patients with COPD underwent spirometry evaluation, body composition by bioelectrical impedance and strength of the quadriceps muscle by the analysis of maximal voluntary contraction (MVC). To test the relationships between indicators forced expiratory volume in one second (FEV1), lean mass (LM) and CVM Pearson correlations were performed. Results: There were significant relationships between FEV1 and MM (r = 0.48, p = 0.02), FEV1 and MVC (r = 0.45, p = 0.05), as well as MM and MVC (r = 0.67, p = 0.002). Conclusion: The results of this study demonstrate that in patients with stable moderate COPD, obstructive respiratory disorder, evidenced by spirometric indicator FEV1 was related to the attributes of mass and peripheral muscle strength, and the decline of force was proportional to muscle mass remaining.