Histologic study of skin of wounds healing using the cream of bacuri (Platonia insignis Mart.)

Abstract

Introduction: The healing process is a sequence of reactions to restore tissue continuity occurs. The bacuri tree (Platonia insignis Mart.) is native to the Amazon, use like antimicrobial and healing action. Objective: To analyze the healing of open wounds and treated with bacuri cream. Methods: We used 46 male Wistar rats. We made up a two-centimeter-diameter wound on the dorsum of all animals which were divided into two groups: the control group and treated and assessed at 4, 7 and 14 days post-operatively. Results: Acute inflammation reduced from seven days in both groups, although it had been more evident in the group treated with the cream. At fourth days both groups did not show any re-epithelialization, the animals treated with the cream on the seventh day showed considerable reepithelialization. Conclusion: The bacuri cream was effective on the seventh day. The fatty acids present in this substance favor the healing process.