Terapia com laser 670nm no tratamento da DPOC experimental em ratos

Wellington dos Santos Alves; Geraldo Cardoso de Oliveira Júnior; Luanna Anielle Evangelista do Santo; Márcia Rejane da Silva Beserra; Flávio Aimbire Soares de Carvalho

doi:10.5585/conssaude.v9i4.2443

Authors

Wellington dos Santos Alves Universidade Estadual do Piaui
Geraldo Cardoso de Oliveira Júnior Faculdade Santo Agostinho
Luanna Anielle Evangelista do Santo Faculdade Santo Agostinho
Márcia Rejane da Silva Beserra Faculdade Santo Agostinho
Flávio Aimbire Soares de Carvalho Universidade Camilo Castelo Branco - UNICASTELO

DOI:

https://doi.org/10.5585/conssaude.v9i4.2443

Keywords:

COPD, Lasers, Lung inflammation, Neutrophils.

Abstract

Introduction: COPD is a respiratory illness with systemic manifestations, characterized by the presence of chronic airflow obstruction associated with an inflammatory response. Objective: To investigate the effect of laser 670nm laser in the treatment of pulmonary inflammation induced in mice. Methods: 30 rats were divided into three groups, two of which were exposed to cigarette smoke for 45 days and one treated with 670 nm laser. For data analysis and ELISA were performed BAL. Results: Results were subjected to analysis of variance (ANOVA) followed by Newman-Keuls test for unpaired samples. BAL analysis showed a highly significant increase in neutrophils in the COPD group. The treated group compared with the COPD group showed a significant decrease in neutrophils. For the result of the ELISA results were highly significant decrease of TNF-α when treated with 670 nm laser, and the significant MIP-2 and IL-1β. Conclusion: It appears that the action of the 670nm laser can attenuate the inflammatory process induced.

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Author Biographies

Wellington dos Santos Alves, Universidade Estadual do Piaui

Formado em Ciências Biológicas, mestre em Bioengenharia, especialista em docência superior e fisiologia do exercício. Professor do curso de fisioterapia da Universidade Estadual do Piaui e da Faculdade Santo Agostinho, Teresina-Pi.