Description of a preparing and application electrode method for cardiophysiological studies in mice

Authors

  • Sarah Soares de Castro UFU
  • Laíse Oliveira Resende UFU
  • Márcia Artiaga Colantoni UFU
  • Lívia Alves Martins UFTM
  • Aldo Rogelis Aquiles Rodrigues UFTM
  • Valdo José Dias UFTM
  • João Batista Destro Filho UFU

DOI:

https://doi.org/10.5585/exactaep.v9n1.2360

Keywords:

Eletrocardiograma, Camundongos, Quetamina, Atropina

Abstract

This paper describes a preparing and application electrode method for cardiophysiological study performed in mice in order to relate the results obtained with these experiments to humans by means of comparative physiology. The study consisted of monitoring the state of mouse cardiophysiological parameters using an electrocardiograph during intravenous administration of subanesthetic ketamine. The final result was obtained by spectral analysis which outlined changes in cardiac activity of the animal after the drug injection, leading to the reduction of RR-interval duration and to the sharp fall in the low frequency (LF) component signal. This result points out that there was an increase in heart rate after pretreatment of atropine and subsequent administration of ketamine.

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Author Biographies

Sarah Soares de Castro, UFU

Faculdade de Engenharia Elétrica/ Laboratório de Engenharia Biomédica

Laíse Oliveira Resende, UFU

Faculdade de Engenharia Elétrica/ Laboratório de Engenharia Biomédica

Márcia Artiaga Colantoni, UFU

Faculdade de Engenharia Elétrica/ Laboratório de Engenharia Biomédica

Lívia Alves Martins, UFTM

UFTM/ Laboratório de Fisiologia

Aldo Rogelis Aquiles Rodrigues, UFTM

UFTM/ Laboratório de Fisiologia

Valdo José Dias, UFTM

UFTM/ Laboratório de Fisiologia

João Batista Destro Filho, UFU

Faculdade de Engenharia Elétrica/ Laboratório de Engenharia Biomédica

Published

2011-06-01

How to Cite

Castro, S. S. de, Resende, L. O., Colantoni, M. A., Martins, L. A., Rodrigues, A. R. A., Dias, V. J., & Destro Filho, J. B. (2011). Description of a preparing and application electrode method for cardiophysiological studies in mice. Exacta, 9(1), 89–101. https://doi.org/10.5585/exactaep.v9n1.2360