Technological cooperation networks and patents in biotechnology: identification of conceptual bases
DOI:
https://doi.org/10.5585/riae.v21i1.21165Keywords:
Innovation, Biotechnology, Bibliometry, Analysis of social networks.Abstract
Objective of the study: This article seeks to explore from bibliometrics with factor analysis, the conceptual bases of the thematic networks of technological cooperation and patents in biotechnology.
Methodology: We performed an exploratory factor analysis (EFA) for quantitative analyses, using the BibExcel software and the Kaiser-Meyer-Olkin test (KMO) (SPSS software). The matrix of citations and quotations resulted in 86 articles, distributed in three factors, according to similarity analysis (Iramuteq software).
Originality/relevance: The term “technological cooperation networks” is increasingly becoming widespread in academia and in the biotechnology sector. However, its concept comes from different theoretical fields, and in the literature, there is still a lack of convergence.
Main results: The matrix of citations and quotations resulted in 86 articles, distributed in three factors, according to similarity analysis (Iramuteq software). The main contribution of the research was the identification of three converging factors, namely: 1) the central role of the biotechnology firm in articulating the knowledge, innovations, and technologies produced and disseminated in the technological cooperation networks; 2) the patent as a valuable resource that concentrates and highlights knowledge, innovations, and technological routes for the firm, its networks, and the industry; and 3) research conceived as a networked activity that promotes the intersection between science produced in universities, technologies conceived in firms, and the dissemination to industry and society of articles, patents, and innovations.
Theoretical/methodological contributions: This study can contribute to the advancement of scientific knowledge by identifying the converging factors of the conceptual field of technological cooperation networks in biotechnology.
Downloads
References
Ahuja, G. (2000). The duality of collaboration: Inducements and opportunities in the formation of interfirm linkages. In Strategic management journal, 21(3), pp. 317-343. https://doi.org/10.1002/(SICI)1097-0266(200003)21:3<317::AID-SMJ90>3.0.CO;2-B.
Ahuja, G., & Katila, R. (2001). Technological acquisitions and the innovation performance of acquiring firms: A longitudinal study. In Strategic management journal, 22(3), pp. 197-220. https://doi.org/10.1002/(SICI)1097-0266(200003)21:3<317::AID-SMJ90>3.0.CO;2-B.
Albert, M. B., Avery, D., Narin, F., & McAllister, P. (1991). Direct validation of citation counts as indicators of industrially important patents. In Research policy, 20(3), pp. 251-259. https://doi.org/10.1016/0048-7333(91)90055-U.
Alcácer, J., Gittelman, M., & Sampat, B. (2009). Applicant and examiner citations in US patents: An overview and analysis. In Research Policy, 38(2), pp. 415-427. https://doi.org/10.1016/j.respol.2008.12.001.
Almeida, P., & Kogut, B. (1999). Localization of knowledge and the mobility of engineers in regional networks. In Management Science, 45(7), pp. 905-917. https://doi.org/10.1287/mnsc.45.7.905.
Araújo, C. A. (2006). Bibliometria: evolução histórica e questões atuais. In Em questão, 12(1), pp. 11-32. Disponível em: https://www.seer.ufrgs.br/index.php/EmQuestao/article/view/16. Acesso em: 19 fev. 2022.
Arya, B., & Lin, Z. (2007). Understanding collaboration outcomes from an extended resource-based view perspective: The roles of organizational characteristics, partner attributes, and network structures. In Journal of management, 33(5), pp. 697-723. https://doi.org/10.1177/0149206307305561.
Balestrin, A., & Verschoore, J. (2016). Redes de Cooperação Empresarial: Estratégias de Gestão na Nova Economia. Porto Alegre: Bookman Editora. ISBN: 8582603983, 9788582603987.
Barbosa, f. v., & Paula, h. c. (2016). Redes de inovação em biotecnologia: relações de parceria e cooperação entre os atores. In III Simpósio Internacional de Gestão de Projetos (SINGEP). Disponível em: http://www.singep.org.br/3singep/resultado/540.pdf. Acesso em: 09 mar. 2022.
Belderbos, R., Carree, M., & Lokshin, B. (2006). Complementarity in R&D cooperation strategies. In Review of Industrial Organization, 28(4), pp. 401-426. https://doi.org/10.1007/s11151-006-9102-z.
Bengtsson, M., & Sölvell, Ö. (2004). Climate of competition, clusters and innovative performance. In Scandinavian Journal of Management, 20(3), pp. 225-244. https://doi.org/10.1016/j.scaman.2004.06.003.
Bogers, M., Zobel, A. K., Afuah, A., Almirall, E., Brunswicker, S., Dahlander, L., ... & Hagedoorn, J. (2017). The open innovation research landscape: Established perspectives and emerging themes across different levels of analysis. In Industry and Innovation, 24(1), pp. 8-40. https://doi.org/10.1080/13662716.2016.1240068.
Broekel, T., & Hartog, M. (2013). Explaining the structure of inter-organizational networks using exponential random graph models. In Industry and Innovation, 20(3), pp. 277-295. https://doi.org/10.1080/13662716.2013.791126.
Boschma, R., Heimeriks, G., & Balland, P. A. (2014). Scientific knowledge dynamics and relatedness in biotech cities. In Research Policy, 43(1), pp. 107-114. https://doi.org/10.1016/j.respol.2013.07.009.
Camargo, B. V., & Justo, A. M. (2013). IRAMUTEQ: um software gratuito para análise de dados textuais. In Temas em psicologia, 21(2), pp. 513-518. https://doi.org/10.9788/TP2013.2-16.
Cockburn, I. M., & Henderson, R. M. (1998). Absorptive capacity, coauthoring behavior, and the organization of research in drug discovery. In The Journal of Industrial Economics, 46(2), pp. 157-182. https://doi.org/10.1111/1467-6451.00067.
Chesbrough, H. W. (2003). Open innovation: The new imperative for creating and profiting from technology. Harvard Business Press. ISBN: 1578518377, 9781578518371.
Chesbrough, H. W., & Appleyard, M. M. (2007). Open innovation and strategy. In California management review, 50(1), pp. 57-76. https://doi.org/10.2307/41166416.
Chesbrough, H., & Bogers, M. (2014). Explicating open innovation: Clarifying an emerging paradigm for understanding innovation. New Frontiers in Open Innovation. In Oxford: Oxford University Press, Forthcoming, pp. 3-28. Available in https://ssrn.com/abstract=2427233. Access: 10 mai. 2022.
Cronin, B. (2001). Bibliometrics and beyond: some thoughts on web-based citation analysis. In Journal of Information Science, 27(1), pp. 1-7. https://doi.org/10.1177/016555150102700101.
Chueke, G. V., & Amatucci, M. (2015). O que é bibliometria? Uma introdução ao fórum. In Internext, 10(2), pp. 1-5. https://doi.org/10.18568/1980-4865.1021-5.
Cohen, W. M., Nelson, R. R., & Walsh, J. P. (2002). Links and impacts: the influence of public research on industrial R&D. In Management science, 48(1), pp. 1-23. https://doi.org/10.1287/mnsc.48.1.1.14273.
Côrtes, M. R., Pinho, M., Fernandes, A. C., Smolka, R. B., & Barreto, A. L. (2005). Cooperação em empresas de base tecnológica: uma primeira avaliação baseada numa pesquisa abrangente. In São Paulo em Perspectiva, 19(1), pp. 85-94. https://doi.org/10.1590/S0102-88392005000100007.
Demirkan, I., & Demirkan, S. (2012). Network characteristics and patenting in biotechnology, 1990-2006. In Journal of Management, 38(6), pp. 1892-1927. https://doi.org/10.1177/0149206311408319.
Da Costa, P. R., Porto, G. S., & Feldhaus, D. (2010). Gestão da cooperação empresa-universidade: o caso de uma multinacional brasileira. In Revista de Administração Contemporânea, 14(1), pp. 100-121. https://doi.org/10.1590/S1415-65552010000100007.
Da Cunha Lemos, D., & Cario, S. A. F. (2017). Os sistemas nacional e regional de inovação e sua influência na interação universidade‐empresa em Santa Catarina. In REGE-Revista de Gestão, 24(1), pp. 45-57. https://doi.org/10.1016/j.rege.2016.05.002.
Desiderio, P. H. M., & Zilber, M. A. (2014). Barreiras no processo de transferência tecnológica entre agências de inovação e empresas: observações em instituições públicas e privadas. In Revista Gestão & Tecnologia, 14(2), pp. 101-126. https://doi.org/10.20397/2177-6652/2014.v14i2.650.
Dias, A. A., & Porto, G. S. (2014). Como a USP transfere tecnologia? In Organizações & Sociedade, 21(70), pp. 489-507. https://doi.org/10.1590/S1984-92302014000300008.
Dyer, J. H., & Singh, H. (1998). The relational view: Cooperative strategy and sources of interorganizational competitive advantage. In Academy of management review, 23(4), pp. 660-679. https://doi.org/10.5465/amr.1998.1255632.
Estrella, A., & Bataglia, W. (2013). A influência da rede de alianças no crescimento das empresas de biotecnologia de saúde humana na indústria brasileira. In Organizações & Sociedade, 20(65). https://doi.org/10.1590/S1984-92302013000200008.
Etzkowitz, H. (1993). Enterprises from science: The origins of science-based regional economic development. In Minerva, 31(3), pp. 326-360. Available in: http://www.jstor.org/stable/41820909. Access: 20 feb. 2022.
Etzkowitz, H. (2013). Anatomy of the entrepreneurial university. In Social Science Information, 52(3), pp. 486-511. https://doi.org/10.1177/0539018413485832.
Etzkowitz, H., & Leydesdorff, L. (1997). Introduction to special issue on science policy dimensions of the Triple Helix of university-industry-government relations. https://doi.org/10.1093/spp/24.1.2.
Etzkowitz, H., & Leydesdorff, L. (2000). The dynamics of innovation: from National Systems and “Mode 2” to a Triple Helix of university–industry–government relations. In Research policy, 29(2), pp. 109-123. https://doi.org/10.1016/S0048-7333(99)00055-4.
Fleming, L., & Sorenson, O. (2004). Science as a map in technological search. In Strategic Management Journal, 25(8‐9), pp. 909-928. https://doi.org/10.1002/smj.384.
Frenken, K., Ponds, R., & Van Oort, F. (2010). The citation impact of research collaboration in science‐based industries: A spatial‐institutional analysis. Papers in regional Science, 89(2), pp. 351-271. https://doi.org/10.1111/j.1435-5957.2010.00309.x.
Groos, O.V. & Pritchard, A. (1969) Documentation notes. Journal of Documentation, Vol. 25 No. 4, pp. 344-349. https://doi.org/10.1108/eb026482.
Guan, J., Zhang, J., & Yan, Y. (2015). The impact of multilevel networks on innovation. In Research Policy, 44(3), pp. 545-559. https://doi.org/10.1016/j.respol.2014.12.007.
Guedes, V. L., & Borschiver, S. (2005). Bibliometria: uma ferramenta estatística para a gestão da informação e do conhecimento, em sistemas de informação, de comunicação e de avaliação científica e tecnológica. In Encontro Nacional de Ciência da Informação, 6(1), pp. 18. Available in: http://www.cinform-anteriores.ufba.br/vi_anais/docs/VaniaLSGuedes.pdf. Access: 20 mar. 2022.
Hagedoorn, J. (1993). Understanding the rationale of strategic technology partnering: Interorganizational modes of cooperation and sectoral differences. In Strategic management journal, 14(5), pp. 371-385. https://doi.org/10.1002/smj.4250140505.
Hair, J., Babin, B., Money, A., & Samouel, P. (2005). Fundamentos de métodos de pesquisa em administração. Bookman Companhia Ed. ISBN: 9788536304496, 8536304499.
Hall, B. H. (2007). Patents and patent policy. Oxford Review of Economic Policy, 23(4), 568-587. https://doi.org/10.1093/oxrep/grm037.
Hall, B. H., Jaffe, A., & Trajtenberg, M. (2005). Market value and patent citations. In RAND Journal of economics, pp. 16-38. Available in: https://escholarship.org/content/qt0cs6v2w7/qt0cs6v2w7.pdf. Access: 09 feb. 2022.
Harhoff, D., Narin, F., Scherer, F. M., & Vopel, K. (1999). Citation frequency and the value of patented inventions. In Review of Economics and statistics, 81(3), pp. 511-515. Available in: https://www.researchgate.net/profile/Dietmar-Harhoff/publication/24095603_Citation_ Frequency_And_The_Value_Of_Patented_Inventions/links/02bfe50f720fb48605000000/Citation-Frequency-And-The-Value-Of-Patented-Inventions.pdf. Access: 10 mar. 2022.
Jaffe, A. B., Trajtenberg, M., & Henderson, R. (1993). Geographic localization of knowledge Spillovers as evidenced by patent citations. In The Quarterly Journal of Economics, 108(3), pp. 577-598. Available in: http://www.iot.ntnu.no/innovation/norsi-common-courses/Lund/JaffeTrajtenbergHenderson93.pdf. Access: 08 feb. 2022.
Jaffe, A. B., & Trajtenberg, M. (2002). Patents, citations, and innovations: A window on the knowledge economy. In MIT Press. ISBN: 026260065X, 9780262600651.
Jensen, R., & Thursby, M. (2001). Proofs and prototypes for sale: The licensing of university inventions. In American Economic Review, 91(1), pp. 240-259. https://doi.org/10.1257/aer.91.1.240.
Katz, J. S., & Hicks, D. (1997). How much is a collaboration worth? A calibrated bibliometric model. Scientometrics, 40(3), pp. 541-554. https://doi.org/10.1007/bf02459299.
Lado, A. A., Paulraj, A., & Chen, I. J. (2011). Customer focus, supply-chain relational capabilities and performance: evidence from US manufacturing industries. In The International Journal of Logistics Management, 22(2), pp. 202-221. https://doi.org/10.1108/09574091111156550
Lerner, J. (1994). The importance of patent scope: an empirical analysis. In The RAND Journal of Economics, pp. 319-333. https://doi.org/10.2307/2555833.
Leydesdorff, L., & Meyer, M. (2006). Triple Helix indicators of knowledge-based innovation systems: Introduction to the special issue. In Research policy, 35(10), pp. 1441-1449. https://doi.org/10.1016/j.respol.2006.09.016.
Marquardt, D. (2013). " Networking" and" New modes of governance" in EU rural development policies-challenges of implementation in Romania. Doctorate Thesis. University of Martin-Luther in Halle-Wittenberg, Management Department. http://dx.doi.org/10.25673/860.
McMillan, G. S., Narin, F., & Deeds, D. L. (2000). An analysis of the critical role of public science in innovation: the case of biotechnology. In Research policy, 29(1), pp. 1-8. https://doi.org/10.1016/S0048-7333(99)00030-X.
Mikhailov, M., & Cooper, R. (2016). Corpus linguistics for translation and contrastive studies: A guide for research. Routledge. https://doi.org/10.4324/9781315624570.
Mowery, D. C., Oxley, J. E., & Silverman, B. S. (1996). Strategic alliances and interfirm knowledge transfer. In Strategic management journal, 17(S2), pp. 77-91. https://doi.org/10.1002/smj.4250171108.
Narin, F., Hamilton, K. S., & Olivastro, D. (1997). The increasing linkage between US technology and public science. In Research policy, 26(3), pp. 317-330. https://doi.org/10.1016/S0048-7333(97)00013-9.
Nederhof, A. J. (2006). Bibliometric monitoring of research performance in the social sciences and the humanities: A review. Scientometrics, 66(1), pp. 81-100. https://doi.org/10.1007/s11192-006-0007-2.
Nerur, S. P., Rasheed, A. A., & Natarajan, V. (2008). The intellectual structure of the strategic management field: An author co‐citation analysis. Strategic Management Journal, 29(3), pp. 319-336. https://doi.org/10.1002/smj.659.
Novelli, M., & Segatto, A. P. (2012). Processo de cooperação universidade-empresa para a inovação tecnológica em um parque tecnológico: evidências empíricas e proposição de um modelo conceitual. In RAI Revista de Administração e Inovação, 9(1), pp. 81-105. https://doi.org/10.5773/rai.v1i1.610.
Okubo, Y. (1997). Bibliometric indicators and analysis of research systems. OECD Science, Technology and Industry Working Papers, No. 1997/01, OECD Publishing, Paris. https://doi.org/10.1787/208277770603.
Oliveira, J. F. G. D., & Telles, L. O. (2011). O papel dos institutos públicos de pesquisa na aceleração do processo de inovação empresarial no Brasil. In Revista USP, (89), pp. 204-217. https://doi.org/10.11606/issn.2316-9036.v0i89p204-217.
Oliver, A. L. (2004). Biotechnology entrepreneurial scientists and their collaborations. In Research Policy, 33(4), pp. 583-597. https://doi.org/10.1016/j.respol.2004.01.010.
Pfaltzgraff, R. L., & Deghand, J. L. (1968). European Technological Collaboration: The Experience of the European Launcher Development Organization (ELDO). In JCMS: Journal of Common Market Studies, 7(1), pp. 22-34. https://doi.org/10.1111/j.1468-5965.1968.tb00206.x.
Pilkington, A., & Meredith, J. (2009). The evolution of the intellectual structure of operations management—1980–2006: A citation/co-citation analysis. In Journal of operations management, 27(3), pp. 185-202. https://doi.org/10.1016/j.jom.2008.08.001.
Pisano, G. (2006). Profiting from innovation and the intellectual property revolution. In Research policy, 35(8), pp. 1122-1130. https://doi.org/10.1016/j.respol.2006.09.008.
Pittaway, L., Robertson, M., Munir, K., Denyer, D., & Neely, A. (2004). Networking and innovation: a systematic review of the evidence. In International journal of management reviews, 5(3‐4), pp. 137-168. https://doi.org/10.1111/j.1460-8545.2004.00101.x.
Powell, W. W., Koput, K. W., & Smith-Doerr, L. (1996). Interorganizational collaboration and the locus of innovation: Networks of learning in biotechnology. In Administrative science quarterly, pp. 116-145. https://doi.org/10.2307/2393988.
Quevedo-Silva, F., Santos, E. B. A., Brandão, M. M., & Vils, L. (2016). Estudo bibliométrico: orientações sobre sua aplicação. In Revista Brasileira de Marketing, 15(2), pp. 246-262. https://doi.org/10.5585/remark.v15i2.3274.
Reinert, P. M. (1987). Classification Descendante Hierarchique et Analvse Lexicale par Contexte-Application au Corpus des Poesies D'A. In Rihbaud. Bulletin of Sociological Methodology/Bulletin de Méthodologie Sociologique, 13(1), pp. 53-90. https://doi.org/10.1177/075910638701300107.
Roper, S., & Love, J. H. (2018). Knowledge context, learning and innovation: an integrating framework. In Industry and Innovation, 25(4), pp. 339-364. https://doi.org/10.1080/13662716.2017.1414744.
Rosenkopf, L., & Almeida, P. (2003). Overcoming local search through alliances and mobility. In Management science, 49(6), pp. 751-766. https://doi.org/10.1287/mnsc.49.6.751.16026.
Sampson, R. C. (2007). R&D alliances and firm performance: The impact of technological diversity and alliance organization on innovation. In Academy of management journal, 50(2), pp. 364-386. https://doi.org/10.5465/amj.2007.24634443.
Santoro, M. D., & Gopalakrishnan, S. (2000). The institutionalization of knowledge transfer activities within industry–university collaborative ventures. In Journal of Engineering and technology management, 17(3-4), pp. 299-319. https://doi.org/10.1016/S0923-4748(00)00027-8.
Santos, S. C.; Sbragia, R.; Toledo, G. O modelo da Hélice Tríplice no desenvolvimento de um Arranjo Produtivo Local de micro e pequenas empresas de base tecnológica. In Revista Científica da FAI, v.12, n.1, 2012, pp. 66-84. Available in: https://www.fai-mg.br/biblio/images/publicacoes/Cientifica/Cientifica2012.pdf. Access: 10 mar. 2022.
Schartinger, D., Rammer, C., & Fröhlich, J. (2006). Knowledge interactions between universities and industry in Austria: sectoral patterns and determinants. In Innovation, networks, and knowledge Spillovers, pp. 135-166. https://doi.org/10.1007/3-540-35981-8_7.
Sebestyén, T., & Varga, A. (2013). Research productivity and the quality of interregional knowledge networks. In The Annals of Regional Science, 51(1), pp. 155-189. https://doi.org/10.1007/s00168-012-0545-x.
Shafique, M. (2013). Thinking inside the box? Intellectual structure of the knowledge base of innovation research (1988–2008). In Strategic Management Journal, 34(1), pp. 62-93. https://doi.org/10.1002/smj.2002.
Small, H., & Garfield, E. (1985). The geography of science: disciplinary and national mappings. In Journal of information science, 11(4), pp. 147-159. https://doi.org/10.1177/016555158501100402.
Schilling, M. A., & Phelps, C. C. (2007). Interfirm collaboration networks: The impact of large-scale network structure on firm innovation. In Management science, 53(7), pp. 1113-1126. https://doi.org/10.1287/mnsc.1060.0624.
Stepanenko, M.G., Pavlov, V.S. (1959). The effect of the boundary arrangement on the thermal balance in the tank-furnace cooling zone. Glass Ceram, v.16, 186–192. https://doi.org/10.1007/BF00667423.
Tödtling, F., Lehner, P., & Kaufmann, A. (2009). Do different types of innovation rely on specific kinds of knowledge interactions? In Technovation, 29(1), pp. 59-71. https://doi.org/10.1016/j.technovation.2008.05.002.
Thompson, G., & Thompson, G. F. (2003). Between hierarchies and markets: the logic and limits of network forms of organization. In Oxford University Press on Demand. . ISBN: 0-19-877527-X, 978-0-19-877527-0.
White, H. D., & McCain, K. W. (1998). Visualizing a discipline: An author co‐citation analysis of information science, 1972–1995. In Journal of the American society for information science, 49(4), pp. 327-355. https://doi.org/10.1002/(SICI)1097-4571(19980401)49:4<327::AID-ASI4>3.0.CO;2-4.
Zucker, L. G., Darby, M. R., & Armstrong, J. (1998). Geographically localized knowledge: Spillovers or markets? In Economic Inquiry, 36(1), pp. 65-86. https://doi.org/10.1111/j.1465-7295.1998.tb01696.x.
Zucker, L. G., Darby, M. R., & Armstrong, J. S. (2002). Commercializing knowledge: University science, knowledge capture, and firm performance in biotechnology. In Management Science, 48(1), pp. 138-153. https://doi.org/10.1287/mnsc.48.1.138.14274.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Revista Ibero-Americana de Estratégia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.