Effects of consuming different doses of red wine on male blood pressure

Everaldo de Araujo Barbosa Filho; Giuliano Elias Pereira; Alfredo Anderson Teixeira-Araújo; Layane Costa Saraiva; Izabelle Silva de Araujo; Wilkslam Alves de Araújo; Reginaldo Luiz do Nascimento; Ferdinando Oliveira Carvalho

doi:10.5585/conssaude.v18n2.11597

Autores

Everaldo de Araujo Barbosa Filho Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0002-4177-9941
Giuliano Elias Pereira Empresa Brasileira de Pesquisa Agropecuária (Embrapa), Petrolina, PE, Brasil. https://orcid.org/0000-0002-0161-8166
Alfredo Anderson Teixeira-Araújo Centro Universitário Dr Leão Sampaio (Unileão), Juazeiro do Norte, CE, Brasil. https://orcid.org/0000-0002-0462-2355
Layane Costa Saraiva Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0001-5151-7294
Izabelle Silva de Araujo Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0001-7588-286X
Wilkslam Alves de Araújo Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0002-3323-4650
Reginaldo Luiz do Nascimento Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0001-6467-0335
Ferdinando Oliveira Carvalho Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. https://orcid.org/0000-0003-0306-5910

DOI:

https://doi.org/10.5585/conssaude.v18n2.11597

Palavras-chave:

Wine, Blood pressure, Men, Blood Pressure Monitoring, Ambulatory.

Resumo

Introduction: Moderate consumption of red wine (RW) has been associated with a decrease in cardiovascular risk due to its phenolic composition. Purpose: Assessing the effects of consuming different doses of RW on the blood pressure (BP) of men during 24 hours after its ingestion. Methods: 10 normotensive male subjects (25.1±3.6 years) consumed three different doses of RW (250ml, 200ml and 150ml) randomly for three weeks; one dose was ingested per week. The BP was measured by using the Ambulatory BP Monitoring every 15 minutes during waking, and every 30 minutes during the sleep period for 24 hours. Results: There was a reduction in mean values of Systolic Blood Pressure (SBP) from six to nine hours of waking period, and the Diastolic Blood Pressure (DBP) from nine to 12 hours of sleep compared with BP at rest. Conclusions: The moderate RW consumption significantly reduced SBP and DBP in men, with a 150ml dose sufficient to reduce and maintain better BP levels.

Downloads

Não há dados estatísticos.

Referências

World Health Organization – WHO [Internet]. Hearts: technical package for cardiovascular disease management in primary health care. Geneva: World Health Organization, 2016. Disponível em: http://www.who.int/cardiovascular_diseases/hearts/Hearts_package.pdf.

Brasil. Departamento de informática do SUS [Internet]. Infarto agudo do miocárdio é primeira causa de mortes no País, revela dados do DATASUS, 2014. Disponível em: http://datasus.saude.gov.br/noticias/atualizacoes/559-infarto-agudo-do-miocardio-e-primeira-causa-de-mortes-no-pais-revela-dados-do-datasus.

De Padua Mansur A, Favarato D. Tendências da Taxa de Mortalidade por Doenças Cardiovasculares no Brasil, 1980-2012. Arquivos Brasileiros de Cardiologia. 2016;107(1):20-25.

Brasil. Ministério da Saúde [Internet]. Secretaria de Atenção à Saúde. Hipertensão arterial sistêmica para o Sistema Único de Saúde. Ministério da Saúde, 2006. Disponível em: http://bvsms.saude.gov.br/bvs/publicacoes/caderno_atencao_basica15.pdf.

Corrêa-Neto VG, Palma A. Pressão arterial e suas associações com atividade física e obesidade em adolescentes: uma revisão sistemática. Revista Ciência & Saúde Coletiva. 2014;19(3):797-818.

Malachias MVB, Souza WKSB, Plavnik FL, et al. 7ª Diretriz Brasileira de Hipertensão Arterial. Arquivos Brasileiros de Cardiologia. 2016;107(3):1-103.

Prado AKM, Caetano MH, Benedetti R. Os efeitos do consumo de vinho na saúde humana. Revista Científica Unilago. 2013;1(1):109-128.8. Chiva-Blanch G, Urpi-Sarda M, Ros E, et al. Dealcoholized red wine decreases systolic and diastolic blood pressure and increases plasma nitric oxide: short communication. Circulation Research. 2012;111(8):1065–1068.

O’Keefe JH, Bhatti SK, Bajwa A, et al. Alcohol and cardiovascular health: the dose makes the poison… or the remedy. Elsevier. 2014;89(3):382-393.

Sabadashka MV, Hnatush AR, Datsiuk LO, et al. The effect of natural polyphenol complex of red grape wine on L-arginine/NO system in peripheral blood of rats under low doses of ionizing radiation. Ukrainian Biochemical Journal. 2013;86(1):117-123.

Ronksley PE, Brien SE, Turner BJ, et al. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. British Medical Journal. 2011;342:d671.

Brito-Filho SBD, Moura EGD, Santos OJD, et al. Effect of chronic ingestion of wine on the glycemic, lipid and body weight homeostasis in mice. Arquivos Brasileiros de Cirurgia Digestiva. 2016;29(3):146-150.

Vaccari de Souza NF, Soccol MCH, Ide GM. Compostos fenólicos em vinhos e seus efeitos antioxidantes na prevenção de doenças. Revista de Ciências Agroveterinárias. 2009;8(1):71-83.

Silva-Padilha CV, Miskinis GA, Souza MEAO, et al. Rapid determination of flavonoids and phenolic acids in grape juices and wines by RP-HPLC/DAD: Method validation and characterization of commercial products of the new Brazilian varieties of grape. Food chemistry. 2017;228;106-115.

Lucena APS, Nascimento RJB, Maciel JAC, et al. Antioxidant activity and phenolics content of selected Brazilian wines. Journal of Food Composition and Analysis. 2010;23(1)30-36.

Luciano MN, Ribeiro TP, França-Silva MS, et al. Uncovering the vasorelaxant effect induced by Vale do Sao Francisco red wine: A role for nitric oxide. Journal of Cardiovascular Pharmacology. 2011;57(6): 696-701.

Droste DW, Iliescu C, Vaillant M, et al. A daily glass of red wine associated with lifestyle changes independently improves blood lipids in patients with carotid arteriosclerosis: results from a randomized controlled trial. Nutrition Journal. 2013;12(1):147-155.

Clemente-Postigo M, Queipo-Ortuño MI, Boto-Ordoñez M, et al. Effect of acute and chronic red wine consumption on lipopolysaccharide concentrations. The American Journal of Clinical Nutrition. 2013;97(5):1053-1061.

Renzo LD, Carraro A, Valente R, et al. Intake of Red Wine in Different Meals Modulates Oxidized LDL Level, Oxidative and Inflammatory Gene Expression in Healthy People: A Randomized Crossover Trial. Oxidative Medicine and Cellular Longevity. 2014;1-9.

World Health Organization - WHO. Obesity: preventing and managing the global epidemic. No. 894. World Health Organization, 2000.

Sociedade Brasileira de Cardiologia. V Diretrizes de Monitoração Ambulatorial Da Pressão Arterial (MAPA) e III Diretrizes de Monitoração Residencial da Pressão Arterial (MRPA). Arquivos Brasileiros de Cardiologia. 2011;97(3):1-2.

Souza AA, França ACL, Bastos VML, et al. Efeito da ingestão de dose única de vinho tinto na hipotensão pós-exercício. Revista Brasileira de Ciências da Saúde. 2014;18(Supl.4):3-10.

Barden AE, Croft KD, Beilin LJ, et al. Acute effects ofred wine oncy to chrome P450 eicosanoids and blood pressure in men. Journal of Hypertension. 2013;31(11):2195–202.

Huang PH, Chen YH, Tsai HY, et al. Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability. Arteriosclerosis, Thrombosis, and Vascular Biology. 2010;30(4):869–877.

Krnic M, Modun D, Budimir D, et al. Comparison of acute effects of red wine, beer and vodka against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans. Atherosclerosis. 2011;218(2):530–535.

Séfora-Sousa M, Angelis-Pereira D. Mecanismos moleculares de ação anti-inflamatória e antioxidante de polifenóis de uvas e vinho tinto na aterosclerose. Revista Brasileira de Plantas Medicinais. 2013;15(4):617-626.

Tresserra-Rimbau A, Medina-Remón A, Lamuela-Raventós RM, et al. Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population. British Journal of Nutrition. 2015;113(Supl.2):121–130.

Barbosa TNRM, Fernandes DC. Compostos bioativos e doenças cardiovasculares: revisando as evidências científicas. Estudos, vida e saúde. 2014;41(2):181-192.

Habauzit V, Morand C. Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: an update for clinicians. Therapeutic Advances in Chronic Disease. 2012;3(2):87-106.

Hollman PCH, Geelen A, Kromhout D. Dietary Flavonol Intake May Lower Stroke Risk in Men and Women. The Journal of Nutrition. 2010;140(3):600-604.