Photodynamic therapy for bactericidal action on venous ulcers of users of public health service

Authors

DOI:

https://doi.org/10.5585/22.2023.23962

Keywords:

Venous ulcer, Photodynamic therapy, low intensity laser therapy

Abstract

Introduction: Ulcers that are difficult to heal are characterized as a pathology that affects about 20 million people around the world. PDT photodynamic therapy is a method that acts in the healing phases, biostimulating the tissue and promoting the death of microorganisms affected by UV.
Methods: To assess the presence of bacteria in the ulcers, a stuart swab was used. the medicine based on curcumin was applied to the ulcer and it was immediately occluded with aluminum foil for 20 minutes.
Results: During the entire collection period, there was growth of bacteria in the ulcers. The participants obtained a reduction in the area of the ulcers, evaluated by the quantification of the Image J software.
Conclusion: PDT was able to accelerate the healing time of venous ulcers, due to its bactericidal effect, the technique still needs further studies.

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Author Biographies

Thalita Cândido Oliveira, Universidade Federal do Triângulo Mineiro

Fisioterapeuta -  Residente no Programa de Residência Multiprofissional Saúde do Adulto da  Universidade Federal do Triângulo Mineiro

Vitoria Helena Maciel Coelho, Universidade Federal do Triângulo Mineiro

Professor Adjunto Departamento de Fisioterapia na Universidade Federal do Triângulo Mineiro

Isabel Aparecida Porcatti Walsh, Universidade Federal do Triângulo Mineiro

Professor Adjunto Departamento de Fisioterapia na Universidade Federal do Triângulo Mineiro

Ana Carolina Silva Ribeiro, Universidade Federal do Triângulo Mineiro

Fisioterapeuta -  Residente no Programa de Residência Multiprofissional Saúde do Adulto da  Universidade Federal do Triângulo Mineiro

Andressa Moreira Marinho, Universidade Federal do Triângulo Mineiro

Enfermeira -  Residente no Programa de Residência Multiprofissional Saúde do Adulto da  Universidade Federal do Triângulo Mineiro

Nathalia Miranda Feitosa Torres, Universidade Federal do Triângulo Mineiro

Biomedicina - Residente no Programa de Residência Multiprofissional Saúde do Adulto da  Universidade Federal do Triângulo Mineiro

References

Pasek J, Szajkowski S, Travagli V, G Cieślar. Topical Hyperbaric Oxygen Therapy Versus Local Ozone Therapy in Healing of Venous Leg Ulcers. Int J Environ Res Public Health. 2023; 20. https://doi.org/10.3390/ijerph20031967

Uttaray S, Vineeth VV, Savlania A , Behera A , Kaman L , Gorsi U. Effect of Endovenous Laser Ablation Along With Compression Therapy on Chronic Venous Ulcer Healing. Cereus. 2023; 15 (1):33406. https://doi.org/10.7759/cureus.33406

Neri CFS, Felis k C, Sandim LS. Venous ulcers : The nurse's approach to nursing consultation. Brazilian Journal of Development. 2020; 6 (5):30682-30694. https://doi.org/10.34117/bjdv6n5-505

Macedo EAB, Araújo RO, Silva RAR, Souza NL, Torres GV. Tratamento hospitalar de pessoas com membros inferiores com varizes e úlceras: pesquisa no DATASUS. Revista Eletrônica da FAINOR. 2018; 11 (3):684-698. https://doi.org/10.11602/1984-4271

Sánchez NNE, Guardado BF, Arriaga CJE, Torres MJA, FloresEM, Serrano LJA. Revisión en úlceras venosas: Epidemiología, fisiopatología, diagnóstico y tratamiento actual. 2019 ; 47 (1): 26-38.

Percival SL, Hill KE, Williams DW, Hooper SJ, Thomas DW, Costerton JW. A review of the scientific evidence for biofilms in wounds. Wound Repair and Regeneration. 2012; 20(5): 647-657.

Dougherty, T.J., et al., Photoradiation therapy for the treatment of malignant tumors. Cancer Res. 1978; 38(8): p. 2628-35. https://doi.org/10.1111/j.1524-475X.2012.00836.x

Babilas P, Karrer S, Sidoroff A, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology--an update. Photodermatol Photoimmunol Photomed. 2005; 21(3):142-9. https://doi.org/10.1111/j.1600-0781.2005.00147.x

Bertoloni G, Sacchetto R, Baro E, Ceccherelli, F. Biochemical andMorphological-Changes in Escherichia-Coli Irradiated by Coherent and Noncoherent 632.8 Nm Light. Journal of Photochemistry and Photobiology B-Biology. 1993; 18(2-3):191-196.

Lehmann P. Side effects of topical photodynamic therapy. Der Hautarzt. 2007; 58(7): 597-603. https://doi.org10.1007/s00105-007-1363-4

Carbinatto F M, Aquino A E, Coelho V H M, Bagnato V S. Photonic technology for the treatments of venous and arterial ulcers: case report. Photodiagnosis And Photodynamic Therapy. 2018; 22: 39-4.http://dx.doi.org/10.1016/j.pdpdt.2018.02.011.

Campoi AL M, Alve S G A, Martins LCN, Barbosa LB, Felicidade P J, Ferreira L A. Assistência de enfermagem a pacientes com feridas crônicas: um relato de experiência. REFACS. 2018; 7 (2): 248-255

Weingarten MS, Branas CC, Czeredarczuk M, Schmidt JD, Wolferth CC Jr. Distribution and quantification of venous reflux in lower extremity chronic venous stasis disease with duplex scanning. J Vasc Surg. 1993;18:753-9.

Cooper RA, Ameen H, Price P, McCulloch DA, Harding KG. A clinical investigation into the microbiological status of 'locally infected' leg ulcers. Int Wound J [Internet]. 2009 [acesso em: 30 jun 2014];6(6):453-62. Disponível em: http://dx.doi.org/10.1111/j.1742-481X.2009.00640.x

Kali A, Srirangaraj S, Kumar S, Divya HA, Kalyani A, Umadevi S. Detection of metallo-beta-lactamase producing Pseudomonas aeruginosa in intensive care units. Australas Med J. 2013;6(12):686-93. http://dx.doi.org/10.4066/AMJ.2013.1824.

Greer N, Foman N, Dorrian J, Fitzgerald P, MacDonald R, Rutks I. Advanced Wound Care Therapies for Non-Healing Diabetic, Venous, and Arterial Ulcers: A Systematic Review Washington: Department of Veterans Affairs; 2012.

Coelho VHM, Alvares LD, Carbinatto FM, Junior AEA, Argarita DPR, Bagnato VS. Photodynamic Therapy, Laser Therapy and Cellulose Membrane for the Healing of 10Venous Ulcers: Results of a Pilot Study. J Nurs Care. 2017. http://dx.doi.org/DOI:.4172/2167-1168.1000387

Carbinatto FM, Junior AEA, Coelho VHM, Bagnato VS. Photonic technology for the treatments of venous and arterial ulcers: Case report. Photodiagnosis and Photodynamic Therapy. 2018; 22: 39-41. https://doi.org/10.1016/j.pdpdt.2018.02.011

Published

2023-11-22

How to Cite

1.
Oliveira TC, Coelho VHM, Walsh IAP, Ribeiro ACS, Marinho AM, Torres NMF. Photodynamic therapy for bactericidal action on venous ulcers of users of public health service. Cons. Saúde [Internet]. 2023 Nov. 22 [cited 2024 Dec. 22];22(1):e23962. Available from: https://periodicos.uninove.br/saude/article/view/23962

Issue

Section

Cases studies