Histomorfologia de órgãos-alvo de ratos diabéticos suplementados com noni (Morinda citrifolia)

Lícia Cândido Soares; Lianna Martha Soares Mendes; karinne Sousa de Araújo; Antonio Luís Martins Maia Filho; Charllyton Luís Sena da Costa; Ísidra Manoela Sousa Portela Santos

doi:10.5585/conssaude.v10i4.2786

Authors

Lícia Cândido Soares Faculdade Integral Diferencial- FACID
Lianna Martha Soares Mendes Universidade Federal do Piauí- UFPI
karinne Sousa de Araújo Faculdade Integral Diferencial-FACID
Antonio Luís Martins Maia Filho Faculdade Integral Diferencial- FACID
Charllyton Luís Sena da Costa faculdade Integral Diferencial- FACID
Ísidra Manoela Sousa Portela Santos Faculdade Integral Diferencial- FACID

DOI:

https://doi.org/10.5585/conssaude.v10i4.2786

Keywords:

Diabetes mellitus, Noni, Phytotherapy.

Abstract

Introduction: Type I Diabetes Mellitus (DM) is a multifactorial disease involving immune response, genetics and the environment. The use of medicinal plants for treatment and prevention of disease is very common; noni (Morinda citrifolia) is an example of one. Objective: To study the effect caused on the kidney, liver and spleen of rats with type I diabetes receiving a daily supplement of noni juice. Methods: A total of 21 rats were divided into three groups of seven animals each: group G0 – healthy animals not receiving the supplement; G1 – type I DM type animals receiving the supplement and G2 – type I DM type animals not receiving the supplement. Results: The spleen and liver showed no pathological changes in any group. Type I diabetic animals not receiving the supplement showed a slight thickening of the glomerular basement membrane. Conclusion: The use of noni juice for a period equal to thirty days does not cause pathological changes in the spleen and liver, but type I diabetic rats receiving the supplement appear to benefit from a nephroprotective effect.